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KMID : 0356019950100020097
Koean Jounral of Critical Care Medicine
1995 Volume.10 No. 2 p.97 ~ p.104
The Effect of Varing Waveforms of Inspiratory Flow on Respiratory System Mechanics and Gas Exchange in Critically ¥²Patients



Abstract
The clinical usefulness of manipulations in inspiratory flow pattern is somewhat unclear and no clear benefit is established one over the other. This study was purposed to evaluate the effect of varing inspiratory flow pattern on the respiratory
system
mechanics and gas exchange. Fourteen patients who received mechanical ventilatory support with a Puritan Bennett 7200ae volume controlled ventilator with CMV mode were evaluated. To measure the respiratory system mechanics, a nasogastric
esophageal
balloon catheter was placed in the lower third of esophagus and connected to the CP-10 Bicore Pulmonary Monitor. Decelerating, square and sine wave flow patterns were evaluated and the peak flow was adjusted to keep mean airway pressure constant.
There
were no significant differences in arterial oxygen tension(PaO2), arterial carbon dioxide tension(PaCO2), dead space ratio(VD/VT), mean airway resistence(RAWM), dynamic compliance(Cdvn) and change in esophageal pressure(dPes) among three
inspiratory
waveforms. But the deceleration waveforin showed the lowest change in peak airway pressure(Dpaw) and the high est respiratory time fraction(T1/Ttot)(p<0.05).
From this study, we suggest that decelerating rlow waveform may reduce the reduce he incidence of ventilator-induced barotrauma during mechanical ventilation.
KEYWORD
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